Severe traumatic brain injury increases the size of intracranial exosomes.

Severe traumatic brain injury induces early changes in the physical properties and protein composition of intracranial extracellular vesicles.

Extracellular vesicles (EVs) are membranous nanostructures that can indicate undergoing processes in organs and thus help in diagnostics and prognostics. They are secreted by all cells, contained in body fluids and able to transfer proteins, lipids and nucleic acids to distant cells. Intracranial EVs were shown to change their composition after severe traumatic brain injury (TBI) and therefore to have biomarker potential to evaluate brain events…more